Preclinical Research
Incidence of Neutralizing Adeno-Associated Viral Antibody Subtypes in Cynomolgus Monkeys
Sinclair Nanopig™: From Multi-Omics Characterization to Toxicology Validation
Tissue Biopsy Collections in Nonhuman Primates During Toxicology Studies
28-Day Intranasal Toxicity Study of MMS019 in Sprague Dawley Rats and Dogs
Q&A With Dr. Norbert Makori and Pierre Jolicoeur: The Benefits of Combining Preclinical and Bioanalytical Solutions for Your Gene Therapy Studies
Recent advances in gene therapy have allowed for diseases to be approached differently. Gene therapy was first discovered in the 1960s, but only gained commercial interest in the 1980s. It wasn’t until 1990 that the first successful gene therapy treatment on a patient transpired.
Pharmacokinetics, Pharmacodynamics and Toxicokinetics Demystified
Understanding the effects of a drug, and how it interacts with the body, and vice versa, is critical to ensure it is safe for human use. This is where pharmacokinetic (PK), pharmacodynamic (PD), and toxicokinetic (TK) analyses step in.
Regulatory Comparisons for Starting First-In-Human Clinical Trials
The Year in Review 2023
Proactive Drug Development for Large Molecules
Introducing Philippine-Origin Cynomolgus Macaque As a Research Model