Preclinical Research
Going Above and Beyond to Exceed Your Expectations
In this new video, our clinical and manufacturing experts share how their teams collaborate and tailor solutions to meet your unique needs. They highlight real examples of going above and beyond by implementing innovative strategies to ensure your projects stay on track.
Looking for a more seamless drug development and manufacturing experience? Speak with one of our experts today.
Related resources that may interest you:
- Video: Nine Strategic Locations to Accelerate Study Timelines
- eBook: Maximizing Drug Formulation for First-in-Human Trials
- Webpage: Pharmaceutical Contract Manufacturing Services
- Podcast: Key Considerations as You Move From Discovery to Preclinical to Clinical
Nonclinical Experts Discuss the Promise of Gene Therapy
Driving Progress in Gene Therapy
Altasciences is a leader in nonclinical research, including gene therapy. In this video, our experts discuss the latest advancements and challenges in the field, while showcasing how our cutting-edge facilities are specifically tailored to support your innovative gene therapy projects.
Want to learn more? Speak with one of our experts.
Related resources that may interest you:
- Webinar: Nonclinical Safety Assessment for Gene Therapy Products
- Scientific Poster: Germline Integration Assessment in Preclinical Gene Therapy Studies
- eBook: Key Considerations for Nonclinical AAV Gene Therapy Development
Evaluate the Impact of Your Drug on Vital Organ Systems
A Full Suite of Safety Pharmacology Capabilities
Altasciences’ safety pharmacology experts can help you prepare a robust program to assess the potential impact of your drug candidate on vital organ systems, including cardiovascular, respiratory, and central nervous systems.
Whether you require the core battery of safety pharmacology tests, drug combination studies, or supplemental studies, you can benefit from our full array of customized solutions and personalized support.
Questions? Speak with one of our experts.
Related resources that may interest you:
- Webpage: Preclinical Research Services
- Video: Safety Pharmacology Validation Data Review
- Podcast: Altasciences’ Scientific Experts Discuss Safety Pharmacology
BioPharma Dive: Pharmaceutical Research on mRNA and CAR T-Cell Therapy in Cancer — Pioneering the Future of Oncology
Essential Guide for Analytical Testing
Fundamental Techniques for Optimal Bioavailability
Analytical testing of active pharmaceutical ingredients (APIs) is critical to ensuring their proper absorption and therapeutic effect. This document examines various analytical techniques that support pharmaceutical product development, with a focus on bioavailability. Methods for API characterization, solubility and dissolution testing, and formulation approaches to maximize bioavailability are discussed.
Altasciences provides contract HPLC/UPLC method development and validation, stability testing, as well as testing of raw materials, in-process, and finished products for your drug development programs. We take pride in developing, qualifying, and validating robust and rugged analytical procedures to ensure the quality of your products and meet the requirements of regulatory agencies worldwide.
Discover our comprehensive suite of drug development and manufacturing services.
Related resources that may interest you:
- Podcast: Ensuring the Successful Manufacturing of Your Clinical Trial Supply
- eBook: Nanomilling for Enhanced Solubility and Bioavailability
- Infographic: Choosing the Optimal Dosage Form for Your Molecule
Latest Findings in Gene Therapy Research
A Promising Future for Gene Therapy
Our experts have been diligently working on groundbreaking research, including a wide range of gene therapy studies, and have compiled a selection of scientific resources featuring the latest advancements.
Bookmark this list for easy reference:
- [Scientific Poster] Historical Review of In-Life Data From Studies Utilizing AAVs for Gene Therapy
- [Scientific Poster] Incidence of Neutralizing Adeno-Associated Viral Antibody Subtypes in Cynomolgus Monkeys of Cambodian, Mauritius, and Philippines Origins
- [Scientific Poster] The Nonhuman Primate Model of CNS Therapies and Utility of Adeno-Associated Viral (AAV) Vectors in Gene Therapy: From Discovery to IND-Enabling Studies
- [Webinar] Nonclinical Adeno-Associated Virus (AAV) Gene Therapy Development―Key Considerations on Study Design and Laboratory Endpoints
- [Webinar] Crucial Aspects in Nonclinical Safety Assessment for Gene Therapy Products
- [Webinar] Cell and Gene Therapy―Enhanced CNS and Ocular Delivery in Nonhuman Primates
- [Scientific Article] Nonclinical Studies in Cell and Gene Therapy
- [Scientific Article] Quantitative PCR (qPCR) and Droplet Digital (ddPCR)―Leading-Edge Analysis for Your Gene Therapy Programs
To learn more about our full range of preclinical research services, speak with one of our experts or visit our website.
Related resources that may interest you:
- Scientific Journal: A Changing Paradigm for Non-Rodent Species in Nonclinical Safety Studies
- Webinar: Best Practices to Reduce Number of Animals Used in Toxicology Studies
- eBook: Safety Assessment of Ophthalmic Products
Accelerated Study Timelines, Less Logistical Hurdles
The True Meaning of Moving in Unison
We value your time as much as you do. At Altasciences, we break down organizational silos, streamline project management, and promote effortless communication to provide you with exceptional value.
From preclinical studies to clinical trials, and from regulatory submissions to tackling operational challenges, we are dedicated to safely accelerating your journey from lead candidate selection to proof of concept and beyond using a seamless and integrated approach to drug development.
Let's get your project started! Speak with an expert today.
Optimize Your Gene Therapy Strategies With This eBook (3 Case Studies Included)
A Comprehensive Guide to Gene Therapy and Improving AAV Efficiency
Entrust your gene therapy research to an experienced CRO like Altasciences.
Our work with CRISPR gene-editing therapeutics in nonhuman primates (NHPs) encompasses a variety of administration routes, supported by our extensive bioanalytical capabilities to conduct biodistribution studies.
Find out more about:
- how to navigate the regulatory landscape;
- how to optimize the safety and efficacy of AAV-based therapies;
- Altasciences’ track record in gene therapy studies; and
- how Altasciences can support your gene therapy studies.
Three supporting case studies are included!
You may also be interested in the below:
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The Altascientist:
- Nonclinical Studies in Cell and Gene Therapy
- Quantitative PCR (qPCR) and droplet digital (ddPCR) for Your Gene Therapy Programs
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Webpages:
- Bioanalytical Services
- Preclinical Services
