Preclinical Research

  • Preclinical Research
  • What Makes Our Pathologists Unique?


    A Chat With Dr. Wendell Davis

    Altasciences’ team of in-house pathologists has expertise with different test articles, drug modalities, and species. With close to 30 years of experience each, our pathologists can support your toxicology studies and help to set safety margins for your clinical trials.

    Watch Dr. Wendell Davis, Vice President of Pathology, explain what makes Altasciences' pathology team unique.


    Learn more about our pathology capabilities:

    Podcast: Digital Pathology―Establishing the Capability
    Press Release: Altasciences Selects Proscia to Accelerate the Development of Life-Saving Drugs

    A Changing Paradigm in Nonclinical Studies

     

    In this issue of The Altascientist, we cover the changing paradigm for non-rodent species selection in nonclinical safety studies, and how the miniature swine is a viable option in small and large molecule studies.

    We discuss:

    Miniature swine size considerations
    Species selection criteria and processes
    Four case studies

    DOWNLOAD NOW

    You may also be interested in the following:

    Webpage: Miniature Swine in Nonclinical Studies
    Webinar: Downsized Miniature Swine: A New Spin on the Oldest Model
    Educational Video: How Do I Select the Right Species for My Toxicology Program?

    A Virtual Tour You Won't Want to Miss!

     

    A Virtual Tour You Won't Want to Miss!

    Step inside our nonclinical facility in Scranton, PA, with this virtual tour. Discover how our expertise in efficacy pharmacology, ophthalmology, and carcinogenicity, to name a few, can support your nonclinical study needs.

    Highlights include:

    - 40 animal rooms
    - Capacity to house ~140 NHPs, ~350 canines, ~350 swine, and ~6,500 rodents
    - On-site archive facility (1,840 sq. ft.)
    - Accreditations/Certifications:​​​​​​
    - AAALAC accredited  
    - USDA registered
    - EPA inspected

    REQUEST A TOUR NOW

    Speak with one of our experts to learn more about our service offering.


    Have five minutes? Take a look at these:

    Webpages: Preclinical Testing Facilities
    Fact Sheet: Preclinical Drug Development
    Webinar: Navigating the Challenges of Early Drug Development

    Development of a Flow Cytometry Phospho-STAT5 Assay in Nonhuman Primate T Cells

    Strategies for Reducing the Number of Animals in Toxicity Testing: A Comparative Approach for Rodent and Large Animal Studies

    Gene Therapy Utilizing Adeno-Associated Viral (AAV) Vectors: Historical Data Review to Characterize Common Challenges and Identify Opportunities for Refinement

    Comparison of Toxicology Assessment Baseline Data Collected Using Two Restraint Methods in Nonhuman Primates: Restraint Chair/Pole and Collar vs. Procedure Cage

    Downsized Sinclair™ vs. Göttingen™ Minipigs Similarities and Differences of Toxicological Reference Range Data in Preclinical Safety Studies

    Ocular Imaging and Microscopic Analysis of Focal Chorioretinal Defects in Rabbits

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