In the complex and dynamic field of metabolic drug development, partnering with an accomplished contract research organization is essential.

Altasciences has over 25 years of experience in metabolic diseases and supports every stage of the development process, from the initial discovery phase and preclinical studies to clinical trials and beyond.

Here are a few highlights:

• The teams at our four preclinical sites are proficient in obesity and metabolic models, and both GLP and non-GLP studies in rodents, dogs, minipigs, and NHPs.
• Our clinical teams have completed over 50 early-stage trials involving anti-diabetic and hypoglycemic agents, such as insulin, GLP-1, SGLT-2, and DPP-4, with 75 type I and type II diabetic patients enrolled in a single-center trial over four weeks.
• Our clinical database includes over 400,000 participants to more quickly qualify for inclusion/exclusion criteria based on pre-existing conditions, demographics, medication use, and BMI.
• Our scientists have developed bioanalytical assays for exenatide, glucagon, insulin glargine (M1, M2), insulin aspart, and metformin.
• We can develop additional assays tailored to your program.
• We’ve conducted numerous pharmacodynamics and immunogenicity assessments, including high-glycemic load challenge/tolerance tests, glucose clamps, insulin-induced hypoglycemic events in type 1 diabetes, and anti-drug antibody evaluations.
• We support data management both at our clinics and at external sites.
• Our pharmacokinetic, pharmacodynamic, and statistical experts support the analysis of drug concentration, biomarker, subjective measure, and immunogenicity data.
• Our medical writers and scientists have designed thousands of studies and are accustomed to preparing clinical protocols and high-quality reports.

Ready to get started? Speak with one of our experts.

You may also be interested in the following resources:

• Webpage: Metabolism and Endocrinology
• The Altascientist: The Many Faces of Metabolic Disorders
• Case Study: Concomitant Administration of Multiple Doses of Cagrilintide With Semaglutide 2·4 mg for Weight Management

Reliable Data for Your Unique Needs

We understand that your research needs are unique, and that's why you can trust us to provide data that aligns with your specific requirements.

Part 1 of our video series reveals how our three laboratories, strategically located across North America and unified by mirrored processes, ensure consistent, reliable results.

This underlines our dedication to scientific excellence and seamless synergies.

Watch part 1!

You may also be interested in the following:

• Altasciences Resource Center (scientific publications, eBooks, webinars, and more!)
• Bioanalytical Services
• Preclinical Services
• Clinical Services

Strategies to Improve Assay Sensitivity to Quantify Therapeutic Oligonucleotides

Are you looking for assays with enhanced sensitivity and minimal sample clean-up in small volumes?

We can help.

Our strategies enhance analytical sensitivity, reduce assay costs, and streamline workflows, optimizing the efficiency and cost-effectiveness of your research and development processes.

Discover this in this real-world example

You may also be interested in the below:

Webinar:

• Bioanalysis by Hybridization ELISA for ASOs

Webpages:

• Bioanalytical Services
• Preclinical Services
• Clinical Services

The True Meaning of Moving in Unison

Join our VP of Global Clinical Operations, Ingrid Holmes, and our VP of Laboratory Sciences, Lynne Le Sauteur, as they share the secrets to the success of our integrated clinical and bioanalytical solution. You won't want to miss this!

Watch the full interview or keep scrolling to jump to a specific section.

1. Proprietary Scheduling System:
   In this video, discover our game-changing, proprietary scheduling system, which is essential for hitting key client deliverables and managing internal milestones across departments and services with precision.
   
   Explore more about our innovative scheduling system here.


2. Advantages of Being a Mid-Sized CRO:
   Flexibility and customized service are at the core of our operations. Our mid-sized stature allows for seamless communication between departments while offering comprehensive services.
   
   Discover the benefits of partnering with a flexible, mid-sized CRO here.


3. Successful Project Case Study:
   In this interview, we highlight a real-world example of a challenging project where seamless communication and coordination, and the proximity of our lab and clinic were pivotal to exceeding client expectations and delivering outstanding results.
   
   See how we tackle complex projects successfully here.

You may also be interested in the following webpages:

• Clinical Research Services
• Bioanalytical Services