With flexible study designs, competitive start times, and on-time reporting, we can help you determine your best candidate.
We can identify the safest molecule as part of your lead candidate selection process through a series of short-term, non-GLP screening studies to detect unusual clinical observations and pathological effects caused by the test articles being compared.
At Altasciences, each lead optimization study is unique and designed on a case-by-case basis by our scientists to meet your needs. Using abbreviated study protocols and summary reports that emphasize the use of tables over text, we aim to deliver important, decision-ready results in the shortest amount of time possible.
Single-dose, 3-5 day and 10-14 day, repeat dose studies are performed to assess the effects of test articles in rodent and non-rodent species. Designs can include multiple test articles in one study to better compare head-to-head results. Assessments usually focus on clinical observations, hematology, gross observations, and pathological evaluations of major organs.
Our deep expertise and capabilities in a broad range of therapeutic areas encompasses preclinical and early clinical studies for both small molecules and biologics. We can manage your entire program, as well as provide comprehensive support research services and bioanalytical expertise.