Bioanalysis
FREE ON-DEMAND WEBINAR—Key Considerations for Nonclinical AAV Gene Therapy
From Screening to PCR Analysis
In this webinar on AAV gene therapy, we explore pre-existing immunity challenges, vector targets, biodistribution, and the role of PCR analysis in assessing therapy efficacy and safety.
Also included are case studies that highlight the delicate balance between innovation and regulatory compliance.
You may also be interested in the following:
The Altascientist
• qPCR and ddPCR—Leading-Edge Analysis for Gene Therapy Programs
• Nonclinical Studies in Cell and Gene Therapy
Webpages
• Bioanalytical Services
• Preclinical Services
Inside The Altascientist: The Benefits of PCR for Your Gene Therapy Programs
The gene therapy landscape continues to accelerate in preclinical and clinical research, with programs constantly in development for targeted, personalized medicines. The goal is to safely incorporate genetic alterations to restore and repair the proteins of missing and/or faulty genes.
Strategies for Safe and Timely Shipments
Your Samples Are in Good Hands With Us!
From regulatory precision to preserving sample integrity, shipments can be challenging. Let us navigate and mitigate these challenges for you with a team of logistical experts to:
• Streamline regulatory compliance through optimized documentation practices.
• Prioritize secure, temperature-controlled shipments with reliable couriers.
• Ensure your samples maintain their integrity with temperature monitoring, robust packaging, and contingency planning.
• Our tailored concierge-style sample shipping ensures your test materials reach the correct destination safely and on time.
You may also be interested in the below resources:
Fact Sheets
Sample Kits
Bioanalytical Services
Webpages
Bioanalytical Services
Clinical Services
Preclinical Services
How Mitra® Vams® Microsampling Device Redefines Sample Collection
From Concept to Application
Delve into the fascinating evolution and revolutionary advancements of the Mitra Vams microsampling device and its applications within life sciences with Dr. James Rudge, Microsampling Technical Director at Neoteryx, and Jeff Plomley, Scientific Director at Altasciences.
Listen now!
Speak with one of our bioanalytical experts today.
Related resources that may interest you:
Microsampling Podcast Series:
Episode 1: When Small Steps Lead to Big Outcomes
Episode 2: Coupling Hybridization LC-MS Workflows With Microsampling
The Altascientist: Microsampling in Drug Development
Webpage: Microsampling in Early Drug Development
Three Platforms Used to Monitor Cytokines and the Complement System
Monitoring both cytokines and complement factors in drug development has become increasingly important, as the movement toward personalized treatments for cancers and genetic diseases has spurred research and development into biologics, vaccines, and small molecules that can have unintended consequences due to their immunomodulatory effects.
Q&A With Dr. Norbert Makori and Pierre Jolicoeur: The Benefits of Combining Preclinical and Bioanalytical Solutions for Your Gene Therapy Studies
Recent advances in gene therapy have allowed for diseases to be approached differently. Gene therapy was first discovered in the 1960s, but only gained commercial interest in the 1980s. It wasn’t until 1990 that the first successful gene therapy treatment on a patient transpired.
Strategic Biomarker Integration
Optimizing Drug Development With Biomarkers
The strategic integration of biomarkers into the drug development process empowers sponsors with critical information at every stage.
Altasciences’ biomarker services provide insight into a drug’s efficacy, safety, and mechanism of action, where we can translate findings into clinical applications and beyond, resulting in reduced timelines.
Our Laboratory Sciences team has the scientific, operational, and regulatory acumen to offer pre-existing validated assays in multiple species and matrices, and can develop new methods to meet your needs.
Is the assay you are looking for missing? Contact us to discuss how we can support your specific needs.
You may also be interested in the below resources:
Fact Sheets
• Flow Cytometry Services
• Immunogenicity Testing
• Immunomodulatory Drugs
eBooks
• Key Biomarkers of Immunomodulation
• Altasciences' Proactive Drug Development Solution: Large Molecules
Poster Presentation
• Immunogenicity Target Interference: A Novel Blocking Approach
Laboratory Sciences Resource Library
A Wealth of Information at Your Fingertips
Explore Altasciences’ bioanalytical resources for comprehensive solutions tailored to your specific requirements. Altasciences’ bioanalytical team specializes in assay development from discovery to preclinical to Phase IV for both small and large molecules.
The Altascientist—A Scientific Journal
The Evolution and Advancement of Liquid Chromatography-Mass Spectrometry in Drug Development. Read or listen to the issue>>>
Validation of Immunogenicity Assays. Read or listen to the issue>>>
Microsampling in Drug Development. Read or listen to the issue>>>
eBook
Key Biomarkers of Immunomodulation. Read or listen to the eBook>>>
Webinars
Uses of Digital Droplet PCR (ddPCR) in Preclinical Research. Watch the webinar>>>
Development of a Cell-Based Assay for Dual Purposes: to Support Drug Potency and Characterize Immunogenicity. Watch the webinar>>>
Speak with an expert today to learn more about our bioanalytical solution.
Have five more minutes? Check out these webpages:
Bioanalytical Services
Assay List