Development of an Assay for Atropine in Rabbit Plasma by LC/MS/MS and the Impact of Atropine Esterase

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Strategies to Improve Assay Sensitivity to Quantify Therapeutic Oligonucleotides

Are you looking for assays with enhanced sensitivity and minimal sample clean-up in small volumes?

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Our strategies enhance analytical sensitivity, reduce assay costs, and streamline workflows, optimizing the efficiency and cost-effectiveness of your research and development processes.

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​​​​Strategies to improve assay sensitivity to quantify therapeutic oligonucleotides

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The Challenges With Outsourcing Drug Development

In a Biopharma Dive survey, 45% of the over 143 biopharmaceutical executives surveyed cited the inability to adhere to tight deadlines as a common challenge in preclinical and Phase I clinical development.

Altasciences Receives 2024 CRO Leadership Award for Capabilities

Laval, Québec, May 29, 2024 – Altasciences announced today that it has been recognized for excellence in contract research with a 2024 CRO Leadership Award for Capabilities. This marks the ninth year that Altasciences, a fully integrated drug development solution company, has been deemed a top performer.

Clinical Leader and Life Science Leader teamed up with ISR Reports to assess 42 CROs on more than 20 performance metrics in ISR’s annual CRO Quality Benchmarking survey. Survey respondents are qualified and only evaluate companies with which they have worked on an outsourced project within the past 18 months.

“For 12 years, Life Science Connect has been working alongside ISR Research to develop our annual CRO Leadership Awards. Receiving one of these awards is a testament to a company’s relentless pursuit of providing the highest standard of service to the clinical research industry, and we congratulate the winners on all their hard work,” said Dan Schell, Chief Editor, Clinical Leader.

The Capabilities category assesses respondents on a CRO’s ability to deliver a wide range of services, expertise, and resources across multiple therapeutic areas. Altasciences has transformed the traditional outsourcing paradigm by building a one-stop outsourcing solution with end-to-end services that simplify and safely accelerate the early-phase drug development process for its clients.

"We are honored to have been recognized as a leader in the CRO industry. Our mission has always been to provide the highest quality early-stage drug development solutions, with personalized services and a focus on efficiency. These awards recognize and validate our employees' daily efforts to achieve our goal. I am incredibly proud of our team," said Chris Perkin, CEO at Altasciences.

With nine strategically placed research and manufacturing facilities across North America, Altasciences helps safely accelerate its clients’ life-changing therapeutics from lead candidate selection to clinical proof of concept, and beyond. 

 

About Altasciences

Altasciences is an integrated drug development solution company offering pharmaceutical and biotechnology companies a proven, flexible approach to preclinical and clinical pharmacology studies, including formulation, manufacturing, and analytical services. For over 25 years, Altasciences has been partnering with sponsors to help support educated, faster, and more complete early drug development decisions. Altasciences’ integrated, full-service solutions include preclinical safety testingclinical pharmacology and proof of conceptbioanalysis, program management, medical writing, biostatistics, clinical monitoring, and data management, all customizable to specific sponsor requirements. Altasciences helps sponsors get better drugs to the people who need them, faster.

 

Media Contact 

Julie-Ann Cabana

Altasciences

+1 514 601-9763

jcabana@altasciences.com  

Discover Our Truly Integrated Clinical and Bioanalytical Solution


The True Meaning of Moving in Unison

Join our VP of Global Clinical Operations, Ingrid Holmes, and our VP of Laboratory Sciences, Lynne Le Sauteur, as they share the secrets to the success of our integrated clinical and bioanalytical solution. You won't want to miss this!

Watch the full interview or keep scrolling to jump to a specific section.

Dr Lynne Le Sauteur and Ingrid Holmes

  1. Proprietary Scheduling System:
    In this video, discover our game-changing, proprietary scheduling system, which is essential for hitting key client deliverables and managing internal milestones across departments and services with precision.

    Explore more about our innovative scheduling system here.

  2. Advantages of Being a Mid-Sized CRO:
    Flexibility and customized service are at the core of our operations. Our mid-sized stature allows for seamless communication between departments while offering comprehensive services.

    Discover the benefits of partnering with a flexible, mid-sized CRO here.

  3. Successful Project Case Study:
    In this interview, we highlight a real-world example of a challenging project where seamless communication and coordination, and the proximity of our lab and clinic were pivotal to exceeding client expectations and delivering outstanding results.

    See how we tackle complex projects successfully here.
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The Sinclair Nanopigᵀᴹ—The Other Non-rodent

Sensitive Quantitation of Antisense Oligonucleotides Using Capitainer® qDBS Microsampling Device Coupled with Hybridization LC-MS/MS

Antisense oligonucleotides—or ASOs—are short, synthetic, single-stranded oligonucleotides  extensively used for altering RNA expression to reduce, restore, or modify protein expression via several distinct mechanisms.

Selecting the Ideal Dosage Form for Your Drug Development Program


Choose Wisely.

With decades of experience developing and manufacturing almost every dosage form on the market, our experts can guide you in selecting the optimal one for your drug development program.

Read the infographic to discover the pros and cons of the two most popular solid oral dosage forms to determine which is best for your molecule.

Ready to discuss your drug development and manufacturing needs? Send us a message.

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Strategies to Improve Assay Sensitivity to Quantify Therapeutic Oligonucleotides

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