Case Study—Accelerating Recruitment in Renal Impairment Trials: Leveraging Specialized External Sites

As a board-certified toxicologist and experienced Good Laboratory Practices (GLP) Consultant, I spend quite a bit of time advising on quality issues of New Approach Methodologies (NAMs) in support of toxicology programs. While these alternative methods are exciting and full of promise, they come with their own set of challenges. 

STAT: Responsible AI Frees Scientists to Focus on Science

The CEO Views: Altasciences—Streamlining Drug Development Decision-Making

CLINDMO: Where Clinical Innovation Meets Manufacturing Excellence

Insights Care: Marie-Hélène Raigneau—Powering a New Era of Early-Phase Drug Development

Time Iconic: Chris Perkin—Transforming Drug Development With Purpose-Driven Leadership and an Industry-Changing Vision

Spray-dried dispersions (SDDs) are an effective method to improve solubility and bioavailability of your active pharmaceutical ingredient (API) in early-phase drug development. The spray drying process involves converting a liquid into a dry powder, with the resulting SDDs benefiting from improved characteristics for further developments. Spray drying can also be combined with nanomilling to further improve the bioavailability, and for flexible downstream processing. 

In Issue 46 of The Altascientist, explore: 

  • how SDDs improve efficiency of early-phase drug development
  • applications and benefits of spray drying in early-phase drug manufacturing
  • advances in spray drying technology for pharmaceutical development
  • the use of spray dry technology in early-phase development of proteins and peptides
  • key considerations for the development of spray-dried pharmaceuticals
 

 

Clinical Trials Without Boundaries: Multi-Site Solutions at Altasciences

Streamlining Cross-Service Line Offerings for Accelerated Drug Development

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