Establishment of Historical Control Reference Values of Cambodian Cynomolgus Macaque Blood Gases

Detection of Plasma Cells and their Precursors in Bone Marrow and Peripheral Blood

Evaluating Cytokine Data in Nonhuman Primate Safety Assessment Studies: A Correlation to Toxicity Outcomes

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Meet Dr. Simone Iwabe, DVM, PhD, DACVO
Senior Veterinary Ophthalmologist

Regulatory processes can be challenging, and potential solutions can be found in broadening your focus to include clinical sites in the U.S. and Canada for your drug development strategy. With an understanding of how regulatory agencies and market environments may differ, you will be in a better position to optimize your program. In Altasciences’ on-demand webinar, A Hop Across the Pond, Ingrid Holmes, Vice President of Global Clinical Operations, and Dr.

In drug development, toxicology evaluates and examines adverse effects of an investigational product on a living organism to determine its initial safety and dose-specific effects. But did you know that toxicology is not limited to drug development? Toxicology is a branch of science that deals with toxins and poisons, and their effects and treatment; other types of toxicology include forensic toxicology, environmental toxicology, food toxicology, and veterinary toxicology.

Take this quiz to discover how much you know (or don’t know) about toxicology.

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The drug development landscape has been evolving over the years, from an earlier emphasis on blockbuster drugs developed in-house by large pharmaceutical companies, t

A crucial feature of drug development is bioavailability, defined as “the ability of a drug to be absorbed and used by the body.” For a drug to be bioavailable, it must first be soluble, meaning able to be dissolved, especially in water. Many drugs on the market today are poorly water soluble, and patent extensions or 505(b)(2) new patents become possible for formulation improvements delivered via nanomilling.

In Issue 22 of The Altascientist, we review: 

  • solubility classifications
  • overcoming solubility challenges
  • the benefits of nanomilling
  • how nanomilling works
  • maximizing formulation

Case study included!

 

 

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