Thanks to updated screening methods and bioavailability enhancements, poorly soluble molecules comprise 70% to 80% of the small molecule products entering the drug development pipeline today. Since poorly soluble drugs are difficult to formulate as tablets, formulation scientists are looking to two-piece, liquid-filled hard-shell capsules as a solution.

Methodological Considerations for the Human Abuse Potential Evaluation of Emerging Drug Therapies with Psychedelic Properties

Key Biomarkers of Immunomodulation: Complement Factors and Cytokines

Quantitation of the COVID-19 Neutralizing Antibody Bamlanivimab* Using Mitra® Microsampling and Mass Spectrometry

Comparing Cytokine Data to In-Life Parameters on Nonhuman Primates in Nonclinical Toxicology Studies

Rapid Development of a Liquid-filled, Hard-Shell Capsule Formulation of Cannabidiol

The Advantages of Liquid-Filled Capsules Over Tablets in All Phases of Drug Development

The quality of study data depends on a rigorous sample management process that safeguards the integrity of samples at every step, from initial specimen collection through bioanalysis, to post-study storage. A CRO partner that conducts both preclinical and clinical studies, and supporting bioanalysis, ensures continuity of processes, knowledge sharing, and a centralized location for long-term storage of all your samples.

Issue 23 of The Altascientist provides a deep dive into: 

  • sample collection and storage conditions
  • standardized workflows for risk Management and chain of custody
  • stability testing
  • laboratory management
  • customized processes
  • management of bioanalytical matrices
  • post-study sample management

 

 

 

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As the incidence of mental health issues increases around the world, most recently exacerbated by the COVID-19 pandemic that has pushed depression to nearly triple the rate

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Tying together the phases of your drug development program are the essential research support services that help your drug candidates not only meet their milestones, but also regulator

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