CNS CENTER OF EXCELLENCEWebinar—CNS-Active Compounds The Importance of Cognitive and Pharmacodynamic Testing During First-In-Human TrialsWebinar—A Square Peg in a Round Hole: Navigating the Unique Attributes of Psychedelic Drug DevelopmentPodcast—FDA Guidance for Industry Psychedelic Drugs Consideration for Clinical InvestigationsWebinar—Navigate the Yellow Brick Road: Practical Approaches to Conducting Early Phase Clinical Trials with Psychedelics.WEBINAR — Inside the Pharmacodynamic Toolbox: How Questionnaires, Models, and Tests of Cognition Can Accelerate the Development of CNS-Active DrugsEducational Video—The Next Trip with Altasciences and DevelRXWebinar — The Many Facets of Early Phase Evaluation of Psychedelics in PsychiatryWebinar — The Brain on Drugs Strategic Use of Cognitive Measures and Biomarkers in Early Phase CNS-Drug StudiesWebinar — Navigating the abuse potential evaluation of CNS-active drugs for EU and US submissionsWebinar — Assessing Cognition and Driving Ability in Clinical Pharmacology StudiesWebinar — Navigating Early Phase CNS-Active Drug Development with Dr. Beatrice Setnik, CSO (1)Webinar — Strategic Considerations for a Successful CNS Clinical Development PathwayWebinar ― Cracking the Pill: A journey of exploring abuse deterrent methods from the laboratory, clinic, and to the real userWebinar — Navigating the ABCs of Early Phase CNS Drug and Cannabinoid Development by Dr. SetnikCONSULTANT SERIESPodcast—Collaborative Innovation: The Role of CROs and CDMOs in Shaping the Future of Drug DevelopmentPodcast—Sparking the Evolution of Microsampling with the Mitra® VAMS® DevicePodcast—Coupling Hybridization LC-MS Workflows With Microsampling for the Analysis of Antisense OligonucleotidesPodcast—Consultant Series: Nonclinical Considerations When Developing an Ophthalmic DrugPodcast — Microsampling: When Small Steps Lead to Big OutcomesPodcast—Emyria, Improving Care for Patients with Unmet Needs with Dr. Michael WinloPodcast — The Importance of a CDMO Consultant with DEL BioPharma and BioPharma ConnectionsPodcast — Consultant Series: Securing VC Funding and Drug Manufacturing ConsultingPodcast — Consultant Series: Chat with Dr. John AtkinsonPodcast — Overcoming Drug Development Pathway Challenges with Dr. Gautam GhatnekarPRECLINICALWebinar—Preclinical Studies of Gene Therapy Products: Latest TrendsWebinar—Innovative Surgical Solutions: Safety Assessment Studies at AltasciencesWebinar—Best Practices to Reduce Animal Use in Toxicology StudiesWebinar—Nonclinical AAV Gene Therapy Development–Key Considerations on Study Design, Laboratory Endpoints, and Regulatory GuidanceWebinar—Sinclair Nanopig™-The Next Generation, Non-Rodent Model for (Bio)Pharmaceuticals Safety AssessmentWebinar—Ocular Imaging Followed by Microscopic Analysis of Focal Chorioretinal Defects in Dutch Belted RabbitsWebinar—Nonclinical Safety Assessment for Gene Therapy Products—Key ConsiderationsWebinar—De-Risking Peripheral Neuropathies With Nerve Conduction: Assay Sensitivity and Avoiding Pitfalls in Signal Collections From Small and Large Animal ModelsWebinar—Gene and Cell Therapy: Enhanced CNS and Ocular Delivery in Nonhuman Primates—Overcoming Technical ChallengesWebinar—Downsized Miniature Swine: A New Spin on the Oldest ModelEducational Video—Digital Pathology: Establishing the CapabilityWebinar—Navigating the Challenges of Early Drug Development—How to Avoid Common PitfallsWebinar — How Do I Select the Right Species for my Toxicology ProgramEducational Video — Avoiding Obstacles When Outsourcing Your Nonclinical ResearchWebinar — Animal Disease Models and Overcoming Technical Challenges Experimentally Induced Hemophilia Type AEducational Video — How to optimize your Safety Pharmacology Studies with Michael GralinskiEducational Video — The Minipig as a Model for Juvenile Toxicity StudiesEducational Video — Beyond the FOB: Considerations for Development of Drugs with Neurologic Side EffectsWebinar — Case Studies Adversity Level Determination in Nonclinical Toxicity StudiesEducational Video — Choosing the Right Model Miniature Swine Model Selection Criteria for Toxicology and Pharmacology StudiesEducational Video — GLP Validation Safety Pharmacology Data ReviewWebinar — Comparison of US FDA and Health Canada CTA submission to Support First-in-Human Phase IPodcast — Altasciences Scientific Experts Discuss Safety PharmacologyWebinar — 2021 SEND Progress UpdateWebinar — SOT 2020 Poster Virtual SessionCLINICALWebinar—A Fork in the Road: Assessing Diversity in Early-Phase Clinical Trials in a Rapidly Changing Regulatory EnvironmentWebinar—The Golden Era of GLP-1 DrugsWebinar—Innovaderm - On The Edge of Dermatology Early Phase TrialEducational Video—Clinkspark OverviewWebinar — Ethnobridging in Phase I Clinical TrialsWebinar—A Hop Across the Pond - Discovering the Many Advantages of Conducting Early Phase Clinical Trials in North AmericaPodcast — COVID-19, Clinical Considerations for Developing TreatmentsPodcast — Choosing the Right CRO for your Clinical Trial MonitoringWebinar — The Heart of the Matter - Early vs. Late QT Prolongation TestingPodcast—Getting a Vaccine to Market with Dr. Beatrice Setnik of AltasciencesBIOANALYSISEducational Video—A Strategic Approach to Microsampling Device Selection and Associated Workflows Supporting Regulated BioanalysisWebinar—Uses of Digital Droplet PCR (ddPCR) in Preclinical ResearchPanel Discussion—Automation in the Bioanalytical LaboratoryWebinar—Development of a Cell-Based Assay for Dual Purposes: to Support Drug Potency and Immunogenicity CharacterizationPodcast—Three Laboratories - One Vision, with Dr. Lynne Le SauteurEducational Video—Altasciences Sample Collection Kits and Laboratory Manual ServicesWebinar — Managing Challenging Bioanalysis for PK/PD assessments for Phase I BiologicWebinar — Bioanalytical Project Management by Dr. Anahita KeyhaniWebinar — A New Dimension by Differential Mobility SpectrometryWebinar — Patient Centricity and the Evolving Role of MicrosamplingEducational Video — Transitioning Novel Scientific Workflows To Routine BioanalysisEducation Video — Importance of sample processing instruction in clinical and preclinical studiesEducation Video — Quantitation of Passive Immunotherapeutic Agents for COVID-19 by LC-MSEducation Video — Certificate of Analysis Essentials for Regulated BioanalysisWebinar — A New Dimension by Differential Mobility SpectrometryWebinar — Bioanalysis by Hybridization ELISA for Antisense OligonucleotidesRESEARCH SERVICESPodcast—Strategic Site Identification: A Proven ApproachWebinar—Determining the Right Regulatory Pathway for Your DrugEducational Video—The Benefits of Conducting a Clinical Trial in CanadaWebinar—The Path Forward, Altasciences’ Approach to Project ManagementWebinar — Comparing CTA Submission (EMA/Health Canada) to IND Applications (FDA) for Phase I TrialsWebinar — Demystifying the Conduct of Clinical Trials in CanadaMANUFACTURING AND ANALYTICAL SERVICESPodcast—Successful Manufacturing of Clinical Trial SupplyPodcast—Tips to Ensure Successful Formulation for Nonclinical TestingPodcast—Key Considerations as you Move from Discovery to Preclinical to ClinicalWebinar—Advantages of Terminal Sterilization Over Aseptic ManufacturingWebinar—The Development of Nanosuspension Formulations for Poorly Soluble DrugsWebinar—Overcoming the Challenges of Manufacturing and Clinical TrialsEducation Video—Altasciences Manufacturing Solutions With Liquid-Filled CapsulesEducation Video—Altasciences’ High-Potency Manufacturing SolutionsTHE MANY FACES OF DRUG USEPODCAST TRAILER — The Many Faces of Drug UsePodcast — The Many Faces of Recreational Drug Use — Episode 3Podcast — The Many Faces of Recreational Drug Use — Episode 2Podcast — The Many Faces of Recreational Drug Use — Episode 1RECORDED POSTER PRESENTATIONSSOT 2025—Evaluation of pH Tolerability in NZ White and Dutch Belted Rabbits Post-IVT AdministrationSOT 2025—Subretinal Injection of Sodium Iodate Creates a Geographic Atrophy-Like Model in NanopigsSOT 2025—A 13-Week Dermal Tox Study of VIM-004 Topical Star Particles in Göttingen Minipigs®SOT 2025—Targeted Gene Therapy for CNS DisordersSOT 2025—Standardization and Harmonization of Altasciences Historical Control Database DevelopmentSOT 2025—Bestrophin-Like Lesions Described in Dutch-Belted RabbitsSOT 2025—Gene Therapy Studies and Germline Integration Assessment in Nonhuman PrimatesACT 2024—Leveraging Nonclinical Safety Evaluation Findings to Expedite Next-Generation GLP-1RAs Development for Metabolic Disorders and BeyondACT 2024—Immunomodulatory Approaches in Preclinical Gene Therapy StudiesACT 2024—Intravenous Sampling and Administration Using Instech Vascular Access Buttons™ in Rodents: Pathology Findings Related to Indwelling Vascular CatheterACT 2024—Intra-Cerebroventricular (ICV) Route in Mice for Administration of Gene Therapy ProductsACT 2024—Lipid Nanoparticles: A Comprehensive Assessment of Liver Enzymes and Immunopathology Markers in Relevant Animal ModelACT 2024—An Examination of the Effects of Body Temperature on QT Interval in Non-Naïve Telemetered Göttingen Minipigs®AALAS 2024—Qualification of a Veterinary Glucometer Use in Yucatan Miniature SwineAAPS 2024 PharmSci 360—Implementation of a Semi-Automated Bead Extraction Procedure During Analyte Purification for High Throughput Immunogenicity AssaysAAPS 2024 PharmSci 360—Development and Validation of LC-MS/MS Assay Methods to Determine Ubrogepant and Atogepant in Human Breast MilkBiosummit 2024—Strategy to Increase Throughput and Method Sensitivity for Clinical Immunogenicity StudiesOTS 2024—Development of a Hybridization LC-MS Methodology for Quantitation of siRNA in Relevant Animal ModelOTS 2024—Strategies to Improve Assay Sensitivity for Bioanalysis of Therapeutic Oligonucleotides Through Ligand Binding AssaysOTS 2024—Quantitative Bioanalysis of HT-KIT Vivo-Morpholino Using Hybridization LC-MS/MSEurotox 2024—T-cell-dependent Antibody Responses and Immunopathology: A Comparative Study in Juvenile Cynomolgus MonkeysEurotox 2024—Incidence of Neutralizing Adeno-Associated Viral Antibody Subtypes in Cynomolgus Monkeys of Cambodian, Mauritius, and Philippines OriginsEurotox 2024—Germline Integration Assessment in Preclinical Gene Therapy StudiesCNS East Xchange 2024—CNS-Targeted Therapies Delivery Strategies and Sampling in Non-rodent Preclinical SpeciesCPDD 2024—Pragmatic Considerations for the Application of Physical Withdrawal Assessments in Patient StudiesCPDD 2024—Development of the Subject-Rated Comprehensive Drug Withdrawal Scale (CDWS)ASMS 2024—Development of an Assay for Atropine in Rabbit Plasma by LC/MS/MS and the Impact of Atropine EsteraseMRF 2024—The Sinclair Nanopigᵀᴹ—The Other Non-rodentAAPS NBC 2024—Sensitive Quantitation of Antisense OligonucleotidesWRIB 2024—Singlicate Analysis in Ligand Binding Assays From Discovery to Regulated Clinical StudiesWRIB 2024—Strategies to Improve Assay SensitivitySQA 2024—Risk-Based Auditing and its Application to GLP Computerized System Validation ProceduresSQA 2024—Collaboration for Success Tips for Improving Partnerships Between QA and Clinical Operations at Your SiteSOT 2024—Comparison of Safety Pharmacology Endpoints Used on Toxicology StudiesSOT 2024—Clinical Pathology Reference Data for Preclinical Toxicology StudiesSOT 2024—Cross-Comparison of Biomarker Assay Performance in Nonhuman PrimatesSOT 2024—Cross-Comparison of Immunophenotyping Assay Performance in Nonhuman PrimatesSOT 2024—Development of a Canine Prostatectomy ModelSOT 2024—Development of a Novel Early Intervention Stabilization for Abdominal Aortic AneurysmsSOT 2024—Historical Background Data in Juvenile Cynomolgus MonkeysSOT 2024—Incidence of Neutralizing Adeno-Associated Viral Antibody Subtypes in Cynomolgus MonkeysSOT 2024—Sinclair Nanopig™: From Multi-Omics Characterization to Toxicology ValidationSOT 2024—Tissue Biopsy Collections in Nonhuman Primates During Toxicology StudiesSOT 2024—28-Day Intranasal Toxicity Study of MMS019 in Sprague Dawley Rats and DogsACT 2023—Introducing Philippine-Origin Cynomolgus Macaque As a Research ModelACT 2023—Proposed Best Practices for Optimizing the Number of Animals in Toxicology StudiesACT 2023—Understanding Species Variation in the Occurrence of Spontaneous Background Eye LesionsACT 2023—Comparison of Cardiovascular and Respiratory Parameters in Three Strains of Research PigsACT 2023—Creation of a Swine Model of Oral AngioedemaACT 2023—Historical Review of In-Life Data From Studies Utilizing AAVs for Gene TherapyACT 2023—Intravenous Sampling and Administration in RodentsAAPS PharmSci360_2023—Retrospective Safety Evaluation of Tyrosine Kinase Inhibitor Products When Administered in Single Dose in Crossover Studies to Healthy VolunteersAAPS PharmSci360_2023—Quantitation of Bemnifosbuvir and Metabolites in Human Bronchoalveolar Lavage by LC-MS/MSAcademy of Surgical Research 2023—Development of a Novel Canine Prostatectomy ModelAPA 2023—Sensitive Quantitation of Antisense Oligonucleotides Using Capitainer® qDBS Microsampling Device Coupled With Hybridization LC-MS/MSCNS Therapeutics Xchange West Coast 2023—The Nonhuman Primate Model of CNS Therapies and Utility of Adeno-Associated Viral (AAV) Vectors in Gene Therapy: From Discovery to IND-Enabling StudiesWRIB 2023—Design and Validation of a Bioanalytical Method to Support a Clinical Pharmacokinetic Study Involving the Use of Multiple Lots of the Biological Therapeutic DrugAAPS NBC 2023—Application of Mitra Microsampling for the Quantitative Bioanalysis of Antisense OligonucleotidesAAPS NBC 2023—Current Strategies for Using Commercial LBA Kit in Regulated BioanalysisSOT 2023—Comparison of Toxicology Assessment Baseline Data Collected Using Two Restraint Methods in Nonhuman Primates: Restraint Chair/Pole and Collar vs. Procedure CageSOT 2023—Correlating Changes in Body Weights and Immune System Parameters in Cynomolgus MacaqueSOT 2023—Development of a Flow Cytometry Phospho-STAT5 Assay in Nonhuman Primate T CellsSOT 2023—Downsized Sinclair™ vs. Göttingen™ Minipigs Similarities and Differences of Toxicological Reference Range Data in Preclinical Safety StudiesSOT 2023—Gene Therapy Utilizing Adeno-Associated Viral (AAV) Vectors: Historical Data Review to Characterize Common Challenges and Identify Opportunities for RefinementSOT 2023—Ocular Imaging and Microscopic Analysis of Focal Chorioretinal Defects in RabbitsSOT 2023—Strategies for Reducing the Number of Animals in Toxicity Testing: A Comparative Approach for Rodent and Large Animal StudiesSOT 2023—Validation of an SC5b-9 Commercial Kit for Preclinical Biomarker AnalysisSQA 2023—Bioanalysis – Three Decades in the MakingSQA 2023—Improving Your Quality Toolbox and Quality MetricsCNS Summit 2022—Inside the Pharmacodynamic Toolbox How Questionnaires, Models, And Tests of Cognition Can Accelerate the Development of CNS-Active DrugsACT 2022—In Vivo and Histological Analysis of Focal Chorioretinal Defects in Dutch Belted RabbitsACT 2022—Establishment of an Induced Hemophilia A Model in Anesthetized Cynomolgus MonkeysACT 2022—A Case Study Comparison of Two Preclinical Studies Utilizing Traditional Versus Modified Methods for Surgical Closing and Post-Operative Treatment for Muscle Biopsy Sites in Nonhuman PrimatesImmunogenicity & Bioassay Summit 2022—Immunogenicity Target Interference: A Novel Blocking ApproachWRIB 2022—A Novel Method for Performing Linearity Assessments in Whole Blood Prepared Using a Lyse No Wash ProcedureWRIB 2022—Development of a Surrogate Cerebrospinal Fluid Matrix for Quantitative Analysis of Antisense Oligonucleotides by Hybridization LC-MS/MSSymposium in Basel: The Opportunity Before Us: How to Navigate for Success in the New Early Phase Development LandscapeThe COVID-19 Pandemic’s Impact on Preclinical Toxicology and Safety Assessment_ Dr Rakesh DixitClinical and Manufacturing Outsourcing Strategy: Impact on the Value of Your Biotech_Benoit Colin and Bruno JacobWe are in the middle of a Cell & Gene Revolution_Dorothea LedergerberHow to Overcome a Crisis and not Let it Go to Waste - a Sponsor’s Tale_ Inge De ClercqImpact of COVID-19 on Clinical Research in the Life Sciences Industry_Dr. MorelliSymposium in Cambridge: Drug Development in the Current ClimateA Message from Chris Perkin, CEO, AltasciencesSinclair Nanopig™: The Next Generation Non-Rodent Model for (Bio)Pharmaceuticals Safety AssessmentReview of Current Regulatory Landscape and Strategic Considerations
