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The Altascientist
THE ALTASCIENTIST JANUARY 2019 ISSUE NO. 7
Effective pharmaceutical therapies — Understanding the intrinsic and extrinsic factors that alter exposure to limit adverse effects and maximize treatment response
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SCIENTIFIC PUBLICATION
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Scientific Publication
The Application of Research Grade MetabolitePilot™ Software for the Determination of Exenatide Catabolites using HRAM with SWATH Acquisition
By:Jeff Plomley1, Yi Zhang2, Eva Duchoslav2, Daniel Villeneuve1, Kevork Mekhssian1 and Anahita Keyhani1.1Altasciences, Laval, Quebec, Canada2SCIEX, Concord, Ontario, CanadaClick on the link below to request this poster's reprint.
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Scientific Publication
Novel In Situ Derivatization Approach for the Sensitive Determination of Menthol in Human Plasma Using Liquid Chromatography Mass Spectrometry
By:Ming-Luan Chen, Milton Furtado and Anahita Keyhani.Click on the link below to request this poster's reprint.
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Scientific Publication
A Novel Strategy for the In-Process Stabilization of N-Oxide Metabolites in Hemolyzed Plasma Determined by LC-MS/MS
By:Richard Lavallée, Georges Koudssi, Milton Furtado and Anahita Keyhani.Click on the link below to request this poster's reprint.
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Scientific Publication
Large Molecule Application of Volumetric Absorptive Microsampling for Single-Rodent PK Profiling of Exenatide Determined by LC-MRM
By:Jeff Plomley1, Daniel Villeneuve1, Mingluan Chen1 Kevork Mekhssian1, Nikolay Youhnovski1, Olivier Didur2, William Ruddock2 and Anahita Keyhani1.1Altasciences, Laval, Quebec, Canada2ITR Laboratories Canada, Montreal, Quebec, CanadaClick on the link below to request this poster's reprint.
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Scientific Publication
Development of an Affinity Capture - LC-MS/MS Assay for the Quantitation of Adalimumab in Human Plasma using BioBA sample preparation kit
By:Jean-François Dupuis1, Kevork Mekhssian1, Ian Moore2, and Anahita Keyhani1.1Altasciences, Laval, Quebec, Canada2SCIEX, Concord, Ontario, CanadaClick on the link below to request this poster's reprint.
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Scientific Publication
Polymeric vs. Diatomaceous Earth SLE Sorbents: A Comparison of Phospholipid Depletion, Matrix Effect and Recovery for Cortisol and 6b-Hydroxycortisol
By:Laurence Mayrand-Provencher, Sylvain Latour, Jeff Plomley, Milton Furtado and Anahita Keyhani.Click on the link below to request this poster's reprint.
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Scientific Publication
Selective Derivatization of Penicillamine Using 5,5′-Dithiobis(2-Nitrobenzoic Acid): Improved Matrix Stability and LC-MS/MS Sensitivity
By:Laurence Mayrand-Provencher, Vinicio Vasquez, Milton Furtado and Anahita Keyhani.Click on the link below to request this poster's reprint.